An up-close image of CBD oil.

December 22


What Is The Half-life Of CBD In Your Body?

By Harrison Payton

December 22, 2021

The Half-life Of CBD

The half-life of CBD is the time it takes for half of the CBD to be eliminated from your body. This half-life is important because it partially determines how long it will take before the effects begin noticeably wearing off or when you can safely take other medications. If the half-life is too short, you may need to increase the dosage or find a different treatment altogether. The half-life of medicines depends on how quickly they are metabolized by the liver and other organs in your body. Join Danu below as we discuss CBD and its half-life in a bit more detail.

What Happens Once CBD Is In The Body?

CBD enters the bloodstream after it is ingested and begins to work within minutes. (It may take half an hour or longer before you may notice a difference.) It interacts with various receptors in the body, including serotonin receptors, CB1, and CB2 endocannabinoid receptors. As a result, CBD influences many different physiological processes, such as pain relief, anxiety relief, anti-inflammatory effects, and in some cases, seizure suppression.

An image of CBD oil.
The half-life of CBD oil can vary greatly depending on the method of consumption.

How Long Does The Half-life Of CBD Last?

The half-life of CBD can vary depending on a person’s weight, metabolism rate, and other health conditions. However, on average, the half-life of CBD is around 24 hours long, but may be one to two days. It’s worth noting the method of CBD intake dramatically affects the half-life. As an example, a cannabidiol oral spray may only last up to about 11 hours, while CBD that has been chronically orally administered may have a half-life of up to 5 days. To explain, this means that if you take 50 mg of CBD oil orally per day, for example, by the end of the third to the fifth day, you will only have 25 mg of active CBD left in your body.

Related Article: How To Minimize THC’s Effects: CBD & More

The Noticeable Effects Vs. The Half-life

While there is a relation, the half-life does not directly equal how long you will feel or potentially benefit from the effects of CBD. It simply means how long before the amount of CBD is only half as detectable in your system. Many people report actually feeling the benefits of CBD for a shorter amount of time. A tincture, for example, may provide relief to some people from 4 to 6 hours. As mentioned above, weight, metabolism, and other factors also come into play, creating a variation between individuals. However, if you are consuming CBD for a specific ailment or health concern, increasing the dosage until you reach the desired effects is recommended.

Can You Safely Take Other Medications With CBD?

Unfortunately, this crucial question depends on many factors and cannot be answered simply. When starting any new medication or natural supplement, it is a great idea to consult with your doctor or other health professional. While CBD has a low occurrence of interacting negatively with other medications, we recommend speaking with a doctor first for your safety.

For Potent And Pure CBD, Consider Danu

Danu‘s primary aim is to help you feel your best by focusing on your natural wellness. We strive to achieve our goal by providing educational resources through our blogs and offering premium third-party lab-tested broad-spectrum cannabidiol products. Extracted from phytocannabinoid-rich hemp grown right here in the United States, Danu’s CBD may be the perfect natural relief alternative you’ve been searching for. Be sure to check out our full selection here!

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